Targeting transdifferentiated hepatic stellate cells and monitoring the hepatic fibrogenic process by means of IGF2R-specific peptides designed in silico
نویسندگان
چکیده
منابع مشابه
Oxymatrine liposome attenuates hepatic fibrosis via targeting hepatic stellate cells.
AIM To investigate the potential mechanism of Arg-Gly-Asp (RGD) peptide-labeled liposome loading oxymatrine (OM) therapy in CCl₄-induced hepatic fibrosis in rats. METHODS We constructed a rat model of CCl₄-induced hepatic fibrosis and treated the rats with different formulations of OM. To evaluate the antifibrotic effect of OM, we detected levels of alkaline phosphatase, hepatic histopatholog...
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ژورنال
عنوان ژورنال: Journal of Materials Chemistry B
سال: 2021
ISSN: 2050-750X,2050-7518
DOI: 10.1039/d0tb02372h